ABSTRACT
Background: As the pandemic of Coronavirus disease (COVID-19) progresses, health care remains a new challenge. The recent rise in second wave possess a different challenge of opportunistic infections especially Mucormycosis in COVID-19 recovered patients. It is complicating their future outcomes and making quality of life more Morbid. Mucormycosis was well known to infect patients with immunocompromised conditions, as the treatment of COVID-19 largely rests on systemic steroids and other immunosuppressant's the risk of invasive fungal infection has increased. Methodology: Here, we present a case series of 07 patients with individual clinical characteristics along with the demography and treatment details studied during 3 months June 2021 to August 2021. The data was collected in a single center that caters to a large population of COVID-19 patients with varying severity in taluka places of Maharashtra. Result(s): seven patients were presented with COVID-19 associated Rhino-orbitocerebral Mucormycosis. The median age was higher in non-survivors (59.5 years), with a higher odds ratio of death (23.8) in those with severe COVID, having overall mortality of 57 %. Moreover, diabetes mellitus was present in 70% of patients with a mortality of 57%. All patients had received prior steroids for COVID-19 management. The incidence of hyperglycemia at admission was equal among both survivors and non-survivors. Conclusion(s): The prevalence of Mucormycosis seems to be more among COVID-19 patients which may be due to with increased use of systemic steroids, and immunocompromised state because by SARS-CoV-2, or conditions such as diabetes mellitus. As the mortality of Mucormycosis is remarkably high and apart from preventive practices and rational use of immunomodulators, a high index of suspicion with early diagnosis is needed. Copyright © 2022 Ubiquity Press. All rights reserved.
ABSTRACT
The aim of this descriptive case series was to determine the frequency of various gastrointestinal symptoms of the COVID-19 patients along with the respiratory symptoms. Secondary outcome was to determine the effect of various co-morbid conditions and various sign and symptoms on the length of hospital stay and outcome of disease Material: In this descriptive case series type study, carried out in the COVID ward in the Jinnah Hospital, Lahore, all patients diagnosed with COVID-19 by consultant physician in the out-patient department and ward were included. Written informed consent was taken from all the participants of the study after explaining the primary objective of the study. The study was carried out from 01-07-2019 to 31-12-2019. Primary objective of this study was to determine the various gastrointestinal symptoms of the COVID-19 patients along with the respiratory symptoms Results: Among the 386 patients enrolled in the study, 60% were male and 40% were female. Mean age of the patients was 54.14 SD 16.3 years, with around 71% cases of age above 45 years. Abdominal pain, anosmia and diarrhea were the most common GI complaints. Over all, 26% of the patients of COVID had GI symptoms. Conclusion(s): GI complaints such as anorexia, nausea, vomiting, diarrhea, and abdominal cramping have been documented in COVID-19 individuals even in the absence of respiratory problems. As a result, COVID-19 disease must be explored in individuals who have mostly GI complaints. Copyright © 2022 Lahore Medical And Dental College. All rights reserved.
ABSTRACT
Aim: To assess the neurological and mental health responses to pandemic Covid-19. Study design: Cohort study Place and duration of study: Department of Medicine, Chandka Medical College Hospital Larkana and Department of Medicine, Khairpur Medical College Hospital Khairpur Mir's from 1st October 2021 to 31st March 2022. Methodology: Two hundred patients who suffered Covid-19 infection and 200 who had any other life event except Covid-19 were enrolled. All patients who were above 18 years of age and were positive for Covid-19 through reverse transcriptase PCR were included in the study.Global Psych trauma Screening was done by enlisting twenty-two items which assessed trauma related symptoms while five items only assessed the factors increasing risks. Result(s): There were 112 (56%) females and 88 (44%) males in Covid-19 patients and 150 (75%) females and 50 (25%) males in non-Covid patients. The mean age of the Covid-19 patients was 49.65+/-15.5 year while of non Covid patients was 39.02+/-12.01 years. A significant increase in post-traumatic stress disorder (PTSD) cases probability was noted in the Covid-19 cases than non Covid-19 related events. Neurological responses showed that patients who had suffered from Covid 19 infections had a generalized weakness with hyposmia formation. Conclusion(s): Covid-19 is related with high level of depression, anxiety, hyposmia and other mental and neurological responses. Copyright © 2022 Lahore Medical And Dental College. All rights reserved.